Tianeptine 25mg x 30ml
Tianeptine is also known as Stablon, Coaxil, Salymbra, Tatinol, Tianeurax, Zinosal
Tianeptine is a research chemical that is classified as an atypical antidepressant which is an antidepressant that acts in an atypical manner compared to the majority of other antidepressant medication. Other atypical antidepressants include nefazodone, trazodone, mirtazapine, bupropion and agomelatine. Tianeptine also has anxiolytic, or antianxiety, effects. Uniquely, the drug relatively lacks the sedative, cardiovascular and anticholinergic side effects that similar substances have shown. It’s dual applications showed in several studies in its early stages of development.
Studies show that tianeptine also acts as a μ-opioid receptor (MOR) atypical agonist. μ-opioid receptors (MOR), also known as μ-opioid peptide (MOP) receptors, have a high affinity for beta-endorphin and enkephalins, but a very low affinity for dynorphins. Morphine, the main psychoactive alkaloid in opium, is a prototypical μ-opioid receptor agonist. Studies showed μ-opioid receptors induce euphoria which caused concerns for abuse.
Molecular formula: C21H25ClN2O4S
CAS number: 66981-73-5
Molar Mass: 436.953 g/mol
PubChem CID: 68870
In the 1960’s, the French Society of Medical Research discovered and then patented the drug Tianeptine. Currently Tianeptine is approved and prescribed in Asia as well as a number of European countries. Laboratories Servier SA manufactures the drug under the name of Coaxil. It is available for research purposes only in the United States.
Tianeptine has has several clinical trials over the years to see the effects on a wide variety of ailments such as depression, anxiety, irritable bowel syndrome, asthma, pain due to fibromyalgia and even attention deficit hyperactivity disorder (ADHD). Past the potential applications that these clinical trials showed, clinical trials also showed several dangers and adverse reactions. The most notable of these was the danger of treatment of Tianeptine when monoamine oxidase inhibitors (MAOIs) are currently being taken or have been taken within at least 14 days prior. This could cause hyperthermia (high body temperature), convulsions, cardiovascular effects (including cardiovascular collapse and hypertension) and even death.