Also known as AOD9604 Peptide, AOD9604
One of the common peptide fragments is AOD9604, and it forms the C-terminus of the Human Growth Hormone by the addition of a Tyrosine at the N-terminal end. AOD9604 has shown tremendous effectiveness in anti-lipogenic activity, and also in stimulating lipolytic (also known as fat burning). AOD9604 has the ability to break down fat and also prevent the transformation of fatty food into stores of body fat) in animals.
Chemical Desctiption of AOD 9604
Molecular formula: C78H123N23O23S2
Molar Mass: 1815.08152
CAS number: 221231-10-3
PubChem: CID 71300630
How AOD 9604 developed from Human Growth Hormone
Scientists of the Monash University revealed that a small region close to the end of the GH Molecule regulated Growth Hormone’s ability to reduce fat. This small region contains amino acids 177-191, which makes up under 10 percent of the entire volume of the GH molecule. The region has no visible, effect on growth resistance or insulin resistance. The way it functions is by replicating how the Natural Growth Hormone regulates Fat metabolism, minus the adverse effects observed with unmodified Growth Hormone.
AOD9604 and it’s Fat loss properties
The effectiveness of AOD9604 as a fat burner was tested on fat cells of pigs, rodents, dogs, and Humans. It showed that the peptide fragment was able to reduce fat from obese fat cells rather than lean fat cells. It also improved fat burning and inhibited fat accumulation and growth in various fat cells. When the same experiment was carried on rats and mice, the peptide fragment reduced the body fats in these rodents, and at the same time enhance the burning of fat stimulating growth or altering the rate of food consumption, or any additional Growth Hormone effect that might not be needed. Results from recent tests and studies show that AOD9604 is an effective fat burner. Some of the functions of AOD9604 also include enhancing muscle mass, increase lip contents in the body, and reducing excessive adipose tissues in the body.
Test Results on AOD 9604’s effects on living cells.
From the results on laboratory mice, AOD9604 led to a short blood glucose increase and a prolonged increase in plasma insulin in combination with peptide fragments 172-191, 177-191 and 178-191. The research also suggests that how the peptides function is dependent on both the physical configuration and informational sequence of the peptide. In addition, AOD9604 is rich in protein, and at the same time has an effect on conformational change observed in the cytoplasmic domain of the band 3 of erythrocyte membrane protein. It achieves this by acting as a base for the pivoting of the two subdomains.